Department Researches & Publications

Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
131 Synthesis, Biological Investigation and Molecular Docking Study of N-Malonyl-1,2-dihydroisoquinoline Derivatives as Brain Specific and Shelf-Stable MAO Inhibitors 2015
132 Synthesis, Biological Investigation and Molecular Docking Study of N-Malonyl-1,2-dihydroisoquinoline Derivatives as Brain Specific and Shelf-Stable MAO Inhibitors 2015
133 Small-Molecule Inhibitors of 25-Hydroxyvitamin D-24-
Hydroxylase (CYP24A1): Synthesis and Biological Evaluation. 		2014
134 Charge-Transfer Reaction of 1,4-Benzoquinone with Crizotinib: Spectrophotometric Study, Computational Molecular Modeling and Use in Development of Microwell Assay for Crizotinib 2014
135 Design and synthesis of new pyrido[2,3-d]pyrimidine-1,4-dione derivatives as anti-inflammatory agents 2014
136 Development of quinone analogues as dynamin GTPase inhibitors 2014
137 High Throughput Microwell Spectrophotometric Assay for Olmesartan Medoxomil in Tablets Based on its Charge-Transfer Reaction with DDQ 2014
138 In Silico Docking, Molecular Dynamics and Binding Energy Insights into the Bolinaquinone-Clathrin Terminal Domain Binding Site 2014
139 Novel Non-Cyclooxygenase Inhibitory Derivatives of Naproxen for Colorectal Cancer Chemoprevention 2014
140 Peptide Arrays for Detecting Naphthenic Acids in Oil Sands Process Affected Water 2014